(Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008].
Li, Ruberu, Karl, Garner: "Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148238, (2016) (PubMed).
Saevarsdottir, Oskarsson, Aspelund, Eiriksdottir, Vikingsdottir, Gudnason, Valdimarsson: "Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk." in: The Journal of experimental medicine, Vol. 201, Issue 1, pp. 117-25, (2005) (PubMed).