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抗Mouse (Murine) MXI1 抗体:
抗Rat (Rattus) MXI1 抗体:
抗Human MXI1 抗体:
The mesangial cell apoptosis observed in this mesangial proliferative glomerulonephritis model was related to CXCL10 (显示 CXCL10 抗体) expression induced by Mxi1 inactivation.
Mxi1 regulates Ift20 (显示 IFT20 抗体) promoter activity via Ets-1 (显示 ETS1 抗体) binding to the Ift20 (显示 IFT20 抗体) promoter. These results indicate that inactivating Mxi1 induces ciliary defects in polycystic kidney.
The results support the suggestion that over-expression of Mxi1 can suppress renal epithelial tubulogenesis.
The results support the suggestion that inactivation of Mxi1 has a positive effect on cell proliferation by down-regulating IGFBP-3 (显示 IGFBP3 抗体).
down-regulation of miR (显示 MLXIP 抗体)-191 is essential for erythroid chromatin condensation and enucleation by allowing up-regulation of Riok3 (显示 RIOK3 抗体) and Mxi1
Mxi1-SRalpha (显示 SRPR 抗体) is an isoform with enhanced transcriptional repression potential
Apolipoprotein A1 (显示 APOA1 抗体) which is a major component of the high-density lipoprotein complex and has anti-inflammation effects, was significantly decreased in the Mxi1-deficient mouse.
Reactive oxygen species mediates hypoxia-induced VEGF (显示 VEGFA 抗体) by upregulation of Mxi1-0.
results suggest that Mxi1-0 regulates the growth of HUVECs via the IL-8 and ERK1/2 pathways, which apparently reciprocally activate each other
MYC (显示 MYC 抗体)-HEG (显示 HEG1 抗体) and MXI1-LEG levels are associated with poor prognosis in patients with breast cancer, suggesting that they may be useful molecular markers in breast cancer prognosis prediction.
MicroRNA-155 promotes glioma cell proliferation via the regulation of MXI1.
MXI1-0 appears to be a downstream target of MYCN (显示 MYCN 抗体)-dependent signaling pathways and may contribute to N-Myc (显示 MYCN 抗体)-dependent cell growth and proliferation.
These findings reveal, for the first time, the novel functions of cooperation of miR243p and miR27a3p from two clusters in promoting cell proliferation through MXI1.
Mxi1 can act as a tumour suppressor in human glioblastomas through a molecular mechanism involving the transcriptional down-regulation of cyclin B1 (显示 CCNB1 抗体) gene expression.
These findings support MXI1 as a putative tumor suppressor gene involved in conventional melanoma progression.
Data show that PTEN and MXI1 were two candidate tumor suppressor genes on 10q23 and 10q24-q25 and may be potentially involved in the initiation and progression of prostate carcinoma.
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
max interactor 1
, MAX interactor 1
, adducin 3 (gamma)
, max-interacting protein 1
, MAX interacting protein 1
, Max interacting protein 1
, MAX dimerization protein 2
, Max-related transcription factor
, class C basic helix-loop-helix protein 11