MXI1 抗体 (Middle Region)
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北京 101111
Quick Overview for MXI1 抗体 (Middle Region) (ABIN2777278)
抗原
See all MXI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- MXI1 Antibody - middle region
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序列
- QGPQEMERIR MDSIGSTISS DRSDSEREEI EVDVESTEFS HGEVDNISTT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against MXI1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MXI1
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anti-MAX Interactor 1 (MXI1) (AA 1-182) antibody
MXI1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-MAX Interactor 1 (MXI1) (Middle Region) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 73-182) antibodyMXI1 适用: 人 WB 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 215-264) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 76-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 170-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 75-173) antibodyMXI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) antibodyMXI1 适用: 人 DB 宿主: 小鼠 Monoclonal MXI1C2a unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104958
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MXI1 (MAX Interactor 1 (MXI1))
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别名
- MXI1
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背景
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Background Information: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors. Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Gene Name: MAX interactor 1
Alternative Symbols: MXI, MAD2, MXD2, bHLHc11
Protein Name: Max-interacting protein 1
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分子量
- 33kDa
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基因ID
- 4601
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NCBI登录号
- NP_569157
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UniProt
- P50539
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途径
- Maintenance of Protein Location
抗原
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