MAX 抗体
(MYC Associated Factor X (MAX))
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Latest Publications for our MAX 抗体
: "lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer." in: Cancer cell, Vol. 33, Issue 4, pp. 706-720.e9, (2019) (PubMed).: "Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus." in: European journal of immunology, Vol. 46, Issue 1, pp. 167-77, (2016) (PubMed).
: "Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X." in: International journal of cancer, Vol. 135, Issue 9, pp. 2054-64, (2014) (PubMed).
: "Max is acetylated by p300 at several nuclear localization residues." in: The Biochemical journal, Vol. 403, Issue 3, pp. 397-407, (2007) (PubMed).
: "HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity." in: Cancer cell, Vol. 11, Issue 4, pp. 335-47, (2007) (PubMed).
: "SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes." in: Molecular cell, Vol. 24, Issue 5, pp. 771-83, (2006) (PubMed).
: "Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32994-9, (2003) (PubMed).
: "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc." in: Science (New York, N.Y.), Vol. 251, Issue 4998, pp. 1211-7, (1991) (PubMed).
Aliases for MAX 抗体
CG9648 gene product from transcript CG9648-RD (Max) 抗体MYC associated factor X L homeolog (max.L) 抗体
MYC associated factor X (MAX) 抗体
MYC associated factor X (max) 抗体
Max protein (Max) 抗体
MYC associated factor X S homeolog (max.S) 抗体
MYC associated factor X (Max) 抗体
myc associated factor X (max) 抗体
AA960152 抗体
AI875693 抗体
bhlhd4 抗体
bHLHd4 抗体
bhlhd5 抗体
bHLHd5 抗体
bhlhd6 抗体
bHLHd6 抗体
bhlhd7 抗体
bHLHd7 抗体
bhlhd8 抗体
bHLHd8 抗体
bHLHd9 抗体
CG9648 抗体
dMax 抗体
dmax 抗体
Dmel\\CG9648 抗体
fa92b04 抗体
fb52a04 抗体
fb95h11 抗体
MAX 抗体
max 抗体
wu:fa92b04 抗体
wu:fb52a04 抗体
wu:fb95h11 抗体
xmax 抗体
xmax2 抗体
xmax4 抗体
zmax 抗体
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