(Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008].
Suyama, Ohashi, Nagai, Hatano, Asano, Murate, Saito, Kinoshita: "The MAGE-A1 gene expression is not determined solely by methylation status of the promoter region in hematological malignancies." in: Leukemia research, Vol. 26, Issue 12, pp. 1113-8, (2002) (PubMed).
Mallon, Platzer, Bate, Gloeckner, Botcherby, Nordsiek, Strivens, Kioschis, Dangel, Cunningham, Straw, Weston, Gilbert, Fernando, Goodall, Hunter, Greystrong, Clarke, Kimberley, Goerdes, Blechschmidt et al.: "Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. ..." in: Genome research, Vol. 10, Issue 6, pp. 758-75, (2000) (PubMed).
Aliases for MAGEA1 抗体
MAGE family member A1 (MAGEA1) 抗体 melanoma antigen, family A, 1 (Magea1) 抗体 CT1.1 抗体 Mage-a1 抗体 MAGE1 抗体