Lysophosphatidic Acid Receptor 1 抗体
(Lysophosphatidic Acid Receptor 1 (LPAR1))
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008].
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Latest Publications for our Lysophosphatidic Acid Receptor 1 抗体
: "Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion." in: Cancers, Vol. 11, Issue 9, (2019) (PubMed).: "Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI." in: Biochemical and biophysical research communications, Vol. 491, Issue 3, pp. 587-594, (2017) (PubMed).
: "Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats." in: Molecular pain, Vol. 12, (2016) (PubMed).
: "Lysophosphatidic acid receptor expression and function in human hepatocellular carcinoma." in: The Journal of surgical research, Vol. 180, Issue 1, pp. 104-13, (2013) (PubMed).
: "Expression of lysophosphatidic acid receptor 1 and relation with cell proliferation, apoptosis, and angiogenesis on preneoplastic changes induced by cadmium chloride in the rat ventral prostate." in: PLoS ONE, Vol. 8, Issue 2, pp. e57742, (2013) (PubMed).
: "Massively parallel sequencing reveals an accumulation of de novo mutations and an activating mutation of LPAR1 in a patient with metastatic neuroblastoma." in: PLoS ONE, Vol. 8, Issue 10, pp. e77731, (2013) (PubMed).
: "Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA)." in: Bioscience reports, Vol. 32, Issue 4, pp. 393-400, (2012) (PubMed).
: "LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells." in: Cancer research, Vol. 71, Issue 23, pp. 7301-11, (2011) (PubMed).
: "Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2." in: Cancer research, Vol. 67, Issue 24, pp. 11751-9, (2007) (PubMed).
: "The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 25, pp. 9643-8, (2006) (PubMed).
Aliases for Lysophosphatidic Acid Receptor 1 抗体
lysophosphatidic acid receptor 1 (LPAR1) 抗体lysophosphatidic acid receptor 1 (Lpar1) 抗体
lysophosphatidic acid receptor 1 (lpar1) 抗体
lysophosphatidic acid receptor 1 S homeolog (lpar1.S) 抗体
lysophosphatidic acid receptor 1 L homeolog (lpar1.L) 抗体
5031439C20 抗体
AI326300 抗体
edg-2 抗体
EDG-2 抗体
EDG2 抗体
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edg2 抗体
edg2-A 抗体
Gpcr26 抗体
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gpr26 抗体
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LPA1 抗体
lpA1 抗体
lpa1 抗体
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lpa1r1 抗体
lpar1 抗体
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VZG1 抗体
vzg1 抗体
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xLPA1-2 抗体
xlpa1R 抗体
zgc:92157 抗体
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