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LPAR1 抗体 (C-Term)

LPAR1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN187787
发货至: 中国
  • 抗原 See all LPAR1 抗体
    LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))
    抗原表位
    • 15
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 42
    • 22
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠
    宿主
    • 43
    • 2
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 20
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LPAR1 antibody is un-conjugated
    应用范围
    • 34
    • 18
    • 13
    • 11
    • 8
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB)
    特异性
    Reacts with EDG-2. Species Reactivity: Human and Rat. Other species not tested.
    过滤
    0.2 μm filtered
    免疫原
    KLH conjugated synthetic peptide corresponding to the AA 328-344 of human EDG-2.
    Top Product
    Discover our top product LPAR1 Primary Antibody
  • 限制
    仅限研究用
  • 缓冲液
    Rabbit polyclonal antibody against human endothelial cell differentiation gene 2 (CT). This antibody is provided as a 0.2 µm sterile-filtered solution in PBS with 0.08% sodium azide at a concentration of 1 mg/mL. Assayed to be >95% purity by SDS PAGE.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))
    别名
    EDG-2 / LPAR1 (LPAR1 产品)
    别名
    EDG2 antibody, GPR26 antibody, Gpcr26 antibody, LPA1 antibody, Mrec1.3 antibody, VZG1 antibody, edg-2 antibody, rec.1.3 antibody, vzg-1 antibody, Edg2 antibody, EDG-2 antibody, 5031439C20 antibody, AI326300 antibody, Kdt2 antibody, lpA1 antibody, edg2 antibody, si:dz22b13.1 antibody, si:dz46m7.1 antibody, zgc:92157 antibody, LPA receptor 1-A antibody, LPA-1-A antibody, gpr26 antibody, lpa1 antibody, lpa1r antibody, lpa1r1 antibody, lpar1 antibody, lpar1-a antibody, lpar1-b antibody, vzg1 antibody, xLPA1-1 antibody, LPA receptor 1-B antibody, LPA-1-B antibody, edg2-A antibody, xLPA1-2 antibody, xlpa1R antibody, lysophosphatidic acid receptor 1 antibody, lysophosphatidic acid receptor 1 S homeolog antibody, lysophosphatidic acid receptor 1 L homeolog antibody, LPAR1 antibody, Lpar1 antibody, lpar1 antibody, lpar1.S antibody, lpar1.L antibody
    背景
    Endothelial cell differentiation gene-2 (EDG-2) receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG-2, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduction decreases in c[AMP]i through Gi and increases in [Ca+2]i by augmenting phospholipase C through Gq/11 and beta/gamma dimers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG-2 is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG-2 receptors (with EDG-4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.
    途径
    Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
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