LEFTY2 抗体
(Left-Right Determination Factor 2 (LEFTY2))
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010].
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58 results
LEFTY2
适用: 人
WB, ELISA
宿主: 兔
Monoclonal
10G210G2
unconjugated
Recombinant Antibody
Latest Publications for our LEFTY2 抗体
: "Spatially organized in vitro models instruct asymmetric stem cell differentiation." in: Integrative biology : quantitative biosciences from nano to macro, Vol. 3, Issue 12, pp. 1179-87, (2011) (PubMed).: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
: "Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21397-404, (2001) (PubMed).
: "Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 5, pp. 343-57, (2000) (PubMed).
: "Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11376-81, (1999) (PubMed).
: "lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal." in: Cell, Vol. 94, Issue 3, pp. 287-97, (1998) (PubMed).
Aliases for LEFTY2 抗体
left-right determination factor 2 (LEFTY2) 抗体left right determination factor 1 (Lefty1) 抗体
lefty2 (lft2) 抗体
left-right determination factor 2 (Lefty2) 抗体
Left-right determination factor 2 (Lefty2) 抗体
left-right determination factor 2 (LOC699676) 抗体
left-right determination factor 2-like (LOC100232580) 抗体
6030463A22Rik 抗体
AI450052 抗体
atv2 抗体
AV214969 抗体
cb720 抗体
EBAF 抗体
Ebaf 抗体
Ebaf2 抗体
fe38b03 抗体
LEFTA 抗体
Lefta 抗体
Leftb 抗体
lefty 抗体
lefty-1 抗体
LEFTYA 抗体
Stra3 抗体
TGFB4 抗体
Tgfb4 抗体
wu:fe38b03 抗体
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