Low Density Lipoprotein Receptor 抗体
(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
Recommended next Filters:
您想试用我们的人工智能搜索吗？
101 results
LDLR
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 兔, 马
WB
宿主: 兔
Polyclonal
unconjugated
1 image
LDLR
适用: 人
WB, FACS, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 reference
LDLR
适用: 人, 小鼠
宿主: 兔
Monoclonal
Alexa Fluor 555
Recombinant Antibody
Latest Publications for our Low Density Lipoprotein Receptor 抗体
: "VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content." in: EMBO reports, Vol. 21, Issue 7, pp. e49343, (2020) (PubMed).: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).
: "Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 188-199, (2019) (PubMed).
: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).
: "Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 6650, (2019) (PubMed).
: "Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr-/-mice." in: Scientific reports, Vol. 7, Issue 1, pp. 17845, (2018) (PubMed).
: "The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins." in: Molecular metabolism, Vol. 16, pp. 88-99, (2018) (PubMed).
: "Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex." in: Scientific reports, Vol. 8, Issue 1, pp. 16845, (2018) (PubMed).
: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).
: "Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol." in: Molecular genetics and metabolism reports, Vol. 10, pp. 11-17, (2017) (PubMed).
Aliases for Low Density Lipoprotein Receptor 抗体
low density lipoprotein receptor (LDLR) 抗体low density lipoprotein receptor (Ldlr) 抗体
low density lipoprotein receptor a (ldlra) 抗体
low density lipoprotein receptor S homeolog (ldlr.S) 抗体
low density lipoprotein receptor L homeolog (ldlr.L) 抗体
FH 抗体
FHC 抗体
fhc 抗体
Hlb301 抗体
LDLA 抗体
LDLCQ2 抗体
ldlcq2 抗体
ldlr 抗体
ldlr-a 抗体
ldlr-b 抗体
ldlr2-a 抗体
LDLRA 抗体
LDL receptor-2 抗体
LDL receptor 1 抗体
您还需要查找其他产品吗？
You are here:
