LASS1 产品
(Ceramide Synthase 1 (CERS1))
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This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1. [provided by RefSeq, Jul 2008].
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Featured LASS1 Categories
Recommended LASS1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN2565661
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7147463
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN564667
Quantity
50 μL
Datasheet
Datasheet
Recommended LASS1 蛋白
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Reactivity
Source
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Quantity
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Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309168
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309170
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3097131
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our LASS1 Products
: "Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice." in: American journal of physiology. Endocrinology and metabolism, Vol. 306, Issue 5, pp. E529-42, (2014) (PubMed).: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).
: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).
: "CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches." in: Electrophoresis, Vol. 33, Issue 24, pp. 3798-809, (2012) (PubMed).
: "Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 1, pp. 296-308, (2010) (PubMed).
: "Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas." in: Molecular cancer therapeutics, Vol. 6, Issue 2, pp. 712-22, (2007) (PubMed).
: "Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a ..." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 35642-9, (2002) (PubMed).
Synonyms and alternative names related to LASS1
ceramide synthase 1 (CERS1), ceramide synthase 1 (Cers1), TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein (LAG1), LAG1, LAG1 HOMOLOG 1, LASS1, Lass1, LONGEVITY ASSURANCE GENE 1, to, Uog-1, UOG1Protein level used designations for LASS1
- longevity assurance gene 1
- longevity assurance (LAG1, S. cerevisiae) homolog 1
- longevity assurance gene 1 protein homolog 1
- protein UOG-1
- upstream of GDF1
- LAG1 homolog, ceramide synthase 1
- LAG1 longevity assurance homolog 1
- longevity assurance homolog 1
- longevity assurance-like protein 1
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