(La Ribonucleoprotein Domain Family, Member 7 (LARP7))
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012].
Egloff, Vitali, Tellier, Raffel, Murphy, Kiss: "The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression." in: The EMBO journal, Vol. 36, Issue 7, pp. 934-948, (2017) (PubMed).
Muniz, Egloff, Kiss: "RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP." in: Nucleic acids research, Vol. 41, Issue 8, pp. 4686-98, (2013) (PubMed).
Aliases for LARP7 抗体
La ribonucleoprotein domain family member 7 (LARP7) 抗体 La ribonucleoprotein domain family, member 7 (Larp7) 抗体 La ribonucleoprotein domain family, member 7 (larp7) 抗体 la-related protein 7 (LOC100222278) 抗体 La ribonucleoprotein domain family member 7 (larp7) 抗体 La ribonucleoprotein domain family, member 7-like (LOC100627397) 抗体 La ribonucleoprotein domain family member 7 (Larp7) 抗体 ALAZS 抗体 C330027G06Rik 抗体 D3Wsu161e 抗体 fa10g04 抗体 LARP7 抗体 PIP7S 抗体 wu:fa10g04 抗体 zgc:56476 抗体