KLLN 产品
(Killin, p53-Regulated DNA Replication Inhibitor (KLLN))
Categories
DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA.
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Featured KLLN Categories
KLLN 抗体
High quality antibodies with extensive validation data.
Recommended KLLN 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7001371
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN655558
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, IHC (p)
Validations
Cat. No.
ABIN872503
Quantity
100 μL
Datasheet
Datasheet
Recommended KLLN 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3082705
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KLLN Products
: "Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma." in: Endocrine-related cancer, Vol. 21, Issue 4, pp. 579-86, (2014) (PubMed).: "Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation." in: Molecular cancer therapeutics, Vol. 13, Issue 2, pp. 517-27, (2014) (PubMed).
: "Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2263-72, (2013) (PubMed).
Synonyms and alternative names related to KLLN
killin, p53-regulated DNA replication inhibitor (KLLN), CWS4, KILLINProtein level used designations for KLLN
- killin
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