KLHL3 产品
(Kelch-Like 3 (KLHL3))
Categories
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)\; a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
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Featured KLHL3 Categories
Recommended KLHL3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
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- (3)
Cat. No.
ABIN7184471
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
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Cat. No.
ABIN6262847
Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN7157290
Quantity
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Recommended KLHL3 ELISA试剂盒
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Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
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Quantity
96 tests
Datasheet
Datasheet
Recommended KLHL3 蛋白
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Reactivity
Source
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Datasheet
Reactivity
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Source
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Validations
- (3)
Cat. No.
ABIN7548790
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
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Validations
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Cat. No.
ABIN7562114
Quantity
1 mg
Datasheet
Datasheet
Reactivity
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Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308817
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our KLHL3 Products
: "Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 19, pp. 7838-43, (2013) (PubMed).Synonyms and alternative names related to KLHL3
kelch like family member 3 (KLHL3), kelch-like 3 (Klhl3), kelch-like family member 3 (Klhl3), 7530408C15Rik, AI430941, EG627648, PHA2D, RGD1565218Protein level used designations for KLHL3
- kelch-like protein 3
- kelch-like 3
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