Helicobacter Pylori Antigen ELISA 试剂盒
适用: Helicobacter pylori
Colorimetric
Sandwich ELISA
0-100 ng/mL
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- 抗原
- Helicobacter Pylori Antigen
- 适用
- Helicobacter pylori
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 0-100 ng/mL
- 最低检测浓度
- 0 ng/mL
- 应用范围
- ELISA
- 原理
- ELISA, Helicobacter pylori Antigen is a quantitative assay for the detection of H. pylori antigens in human stool specimen.
- Analytical Method
- Quantitative
- 灵敏度
- 0.5 ng/mL
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- 实验时间
- 1 - 2 h
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
- 有效期
- 12-18 months
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- 抗原
- Helicobacter Pylori Antigen
- 背景
- Helicobacter pylori is a spiral bacterium cultured from human gastric mucosa by Marshall in 1982. Studies have indicated that the presence of H. pylori is associated with a variety of gastrointestinal diseases including gastritis, duodenal and gastric ulcer, non-ulcer dyspepsia, gastric adenocarcinoma and lymphoma. The organism is present in 95-98% of patients with duodenal ulcer and 60-90% of patients with gastric ulcers. The studies have also demonstrated that removal of the organism by antimicrobial therapy is correlated with the resolution of symptoms and cure of diseases. Patients who present with clinical symptoms relating to the gastrointestinal tract can be diagnosed for H. pylori infection by two methods: 1) Invasive techniques include biopsy followed by culture or histological examination of biopsy specimen or direct detection of urease activity. The cost and discomfort to the patients are very high and biopsy samples are subject to errors related to sampling and interference of contaminated bacteria. 2) Non-invasive techniques include urea breath tests (UBT) and serological methods. The UBT requires a high density and active bacteria and should not be performed until 4 weeks after therapy to allow resisdual bacteria to increase to the detection level. The main limitation of serology test is the inability to distinguish current and past infections.
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