IGFBP3 ELISA 试剂盒
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- 抗原 See all IGFBP3 ELISA试剂盒
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
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适用
- 小鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 156 pg/mL - 10000 pg/mL
- 最低检测浓度
- 156 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Supernatant, Serum
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: Acid stable subunit of the 140 K IGF complex, Binding protein 29, Binding protein 53, BP 53, BP53, Growth hormone dependent binding protein, IBP 3, IBP3, IGF binding protein 3, IGFBP 3, Insulin Like Growth Factor Binding Protein 3
Background: Insulin-like growth factor(IGF)-binding protein-3(IGFBP-3) is a major determinant of circulating levels of the IGFs and is clinically useful for the evaluation of GH deficiency and for predicting the response to GH treatment. The circulating level of IGFBP-3 is inversely related to the risk of several common cancers, and that antiproliferative agents such as antiestrogens and retinoids act in part by up-regulating IGFBP-3 gene(IGFBP3) expression. Insulin-like growth factor-binding protein(IGFBP)-3, well characterized as the carrier of insulin-like growth factor(IGF), has been reported to have intrinsic bioactivity that is independent of IGF binding. IGFBP-3 has an IGF-independent, antiproliferative effect in undifferentiated and early differentiated but not in terminally differentiated chondrocytes. IGFBP-3 possesses both growth-inhibitory and potentiating effects on cells that are independent of IGF action and are mediated through specific. IGFBP-3 binding proteins/receptors locate at the cell membrane, cytosol, or nuclear compartments and in the extrIGFBP-3llular matrix. IGFBP3 is also located on chromosome 7. The standard product used in this kit is recombinant mouse IGFBP-3, consisting of 270 amino acids with the molecular mass of 29.4 kDa. As a result of glycosylation, the molecular mass is 40-50KDa.
Gene Name: IGFBP3
Production: Natural and recombinant mouse IGFBP-3. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: G28Q-K291
- Top Product
- Discover our top product IGFBP3 ELISA Kit
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Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA Kit
IGFBP3 适用: 人 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: 大鼠 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: Pig Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: 小鼠 Colorimetric Sandwich ELISA 0.94 ng/mL - 60 ng/mL Plasma, Serum
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: 小鼠 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Plasma, Serum, Tissue Homogenate
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: 小鼠 Colorimetric Sandwich ELISA 31.25 ng/mL - 2000 ng/mL Cell Culture Supernatant, Plasma, Serum
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: 小鸡 Colorimetric Competition ELISA 6.25 ng/mL - 400 ng/mL Plasma, Serum, Tissue Homogenate
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: 犬 Colorimetric Sandwich ELISA 3.12 ng/mL - 200 ng/mL Plasma, Serum, Tissue Homogenate
Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) ELISA KitIGFBP3 适用: Cow Colorimetric Sandwich ELISA 0.62 ng/mL - 40 ng/mL Plasma, Serum, Tissue Homogenate
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 313pg/mL, 156pg/mL mouse IGFBP-3 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernates or serum to each empty well. It is recommended that each mouse IGFBP-3 standard solution and each sample be measured in duplicate.
ELISA Dilution: 156pg/mL-10000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- 抗原 See all IGFBP3 ELISA试剂盒
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- 别名
- IGFBP-3 (IGFBP3 产品)
- 别名
- BP-53 ELISA Kit, IBP3 ELISA Kit, AI649005 ELISA Kit, IGFBP-3 ELISA Kit, IGgfbp3 ELISA Kit, IGF-BP3 ELISA Kit, zgc:91788 ELISA Kit, IGFBP3 ELISA Kit, igfbp3 ELISA Kit, insulin like growth factor binding protein 3 ELISA Kit, insulin-like growth factor binding protein 3 ELISA Kit, IGFBP3 ELISA Kit, Igfbp3 ELISA Kit, igfbp3 ELISA Kit, IGFBP-3 ELISA Kit, LOC100305016 ELISA Kit
- 基因ID
- 3486
- NCBI登录号
- NP_000589
- UniProt
- B3KPF0
- 途径
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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