ICOS ELISA 试剂盒
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Quick Overview for ICOS ELISA 试剂盒 (ABIN5692214)
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See all ICOS ELISA试剂盒抗原表位
适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 62.5 pg/mL
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human ICOS. 96wells/kit, with removable strips.
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Analytical Method
- Quantitative
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特异性
- Expression system for standard: NSO, Immunogen sequence: E21-F141
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灵敏度
- < 2 pg/mL
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组件
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover
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Inducible T-Cell Co-Stimulator (ICOS) ELISA Kit
ICOS 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Inducible T-Cell Co-Stimulator (ICOS) ELISA KitICOS 适用: 大鼠 Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Inducible T-Cell Co-Stimulator (ICOS) ELISA KitICOS 适用: 人 Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Cell Lysate, Plasma, Serum, Urine
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实验时间
- 15 min
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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别名
- ICOS
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背景
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Synonyms: Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD278, ICOS, AILIM
Tissue Specificity: Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B- cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus.
Background: Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene. The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Cellular Localisation: Isoform 1: Cell membrane, Single-pass type I membrane protein. -
UniProt
- Q9Y6W8
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途径
- Cancer Immune Checkpoints
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