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IL-24 ELISA 试剂盒

IL24 适用: 小鼠 AA 27-181 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN5692204
发货至: 中国
  • 抗原 See all IL-24 (IL24) ELISA试剂盒
    IL-24 (IL24) (Interleukin 24 (IL24))
    抗原表位
    AA 27-181
    适用
    • 4
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    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    62.5 pg/mL - 4000 pg/mL
    最低检测浓度
    62.5 pg/mL
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse IL-24. 96wells/kit, with removable strips.
    品牌
    PicoKine™
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: E.coli, Immunogen sequence: Q27-L181
    灵敏度
    < 10 pg/mL
    组件
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
    Featured
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    Discover our top product IL24 ELISA Kit
  • 实验时间
    0.5 h
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all IL-24 (IL24) ELISA试剂盒
    IL-24 (IL24) (Interleukin 24 (IL24))
    别名
    Il24 (IL24 产品)
    别名
    C49A ELISA Kit, FISP ELISA Kit, IL10B ELISA Kit, MDA7 ELISA Kit, MOB5 ELISA Kit, ST16 ELISA Kit, Mda7 ELISA Kit, St16 ELISA Kit, Mda-7 ELISA Kit, IL24 ELISA Kit, interleukin 24 ELISA Kit, IL24 ELISA Kit, Il24 ELISA Kit
    背景

    Synonyms: Interleukin-24, IL-24, Melanoma differentiation-associated gene 7 protein, MDA-7, Suppression of tumorigenicity 16 protein, IL24, MDA7, ST16

    Tissue Specificity: Up-regulated in melanoma cells induced to terminally differentiate.

    Background: Interleukin 24 (IL-24) is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as Melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. By radiation hybrid analysis, the MDA7 gene is mapped to 1q32.2-q41. IL-24 appears to control in cell survival and proliferation by inducing rapid activation of particular transcription factors called Stat-1 and Stat-3. Mouse IL24 was expressed as an approximately 35-kD protein that was converted to a 23-kD protein by deglycosylation. The IL24 protein shares 24 to 33 % homology with other members of the IL10 family of cytokines, with highest homology with IL20. This cytokine is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer.

    Cellular Localisation: Secreted.
    UniProt
    Q13007
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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