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IL-24 ELISA 试剂盒

This 小鼠 IL-24 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 IL-24.
产品编号 ABIN5692204
发货至: 中国

Quick Overview for IL-24 ELISA 试剂盒 (ABIN5692204)

抗原

See all IL-24 (IL24) ELISA试剂盒
IL-24 (IL24) (Interleukin 24 (IL24))

抗原表位

AA 27-181

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

62.5 pg/mL - 4000 pg/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
  • 最低检测浓度

    62.5 pg/mL

    原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse IL-24. 96wells/kit, with removable strips.

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: E.coli, Immunogen sequence: Q27-L181

    灵敏度

    < 10 pg/mL

    组件

    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
  • 实验时间

    0.5 h

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • 抗原 See all IL-24 (IL24) ELISA试剂盒

    IL-24 (IL24) (Interleukin 24 (IL24))

    别名

    Il24

    背景

    Synonyms: Interleukin-24, IL-24, Melanoma differentiation-associated gene 7 protein, MDA-7, Suppression of tumorigenicity 16 protein, IL24, MDA7, ST16

    Tissue Specificity: Up-regulated in melanoma cells induced to terminally differentiate.

    Background: Interleukin 24 (IL-24) is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as Melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. By radiation hybrid analysis, the MDA7 gene is mapped to 1q32.2-q41. IL-24 appears to control in cell survival and proliferation by inducing rapid activation of particular transcription factors called Stat-1 and Stat-3. Mouse IL24 was expressed as an approximately 35-kD protein that was converted to a 23-kD protein by deglycosylation. The IL24 protein shares 24 to 33 % homology with other members of the IL10 family of cytokines, with highest homology with IL20. This cytokine is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer.

    Cellular Localisation: Secreted.

    UniProt

    Q13007

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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