Prostate Specific Antigen ELISA 试剂盒
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Quick Overview for Prostate Specific Antigen ELISA 试剂盒 (ABIN5526768)
抗原
See all Prostate Specific Antigen (PSA) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 0.04 ng/mL
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原理
- This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human PSA.
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Analytical Method
- Quantitative
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特异性
- PSA
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组件
- plate, standard, diluent
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试剂未包括
- pipettes, tubes, reader
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样本量
- 100 μL
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实验时间
- 3 - 4 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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缓冲液
- 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- Prostate Specific Antigen (PSA)
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别名
- KLK3
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背景
- Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. Obesity has been reported to reduce serum PSA levels. PSA levels can be also increased by prostatitis, irritation and benign prostatic hyperplasia producing a false positive result. PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy. Clinical practice guidelines for prostate cancer screening vary and are controversial due to uncertainty as to whether the benefits of screening ultimately outweigh the risks of overdiagnosis and over treatment.
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NCBI登录号
- NM_001030047
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UniProt
- P07288
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途径
- Complement System
抗原 See all Prostate Specific Antigen (PSA) ELISA试剂盒
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