IL-25 ELISA 试剂盒
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Quick Overview for IL-25 ELISA 试剂盒 (ABIN5526765)
抗原
See all IL-25 (IL25) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 2.39 pg/mL
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原理
- This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-17E.
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Analytical Method
- Quantitative
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特异性
- IL-17E
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组件
- plate, standard, diluent
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试剂未包括
- pipettes, tubes, reader
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样本量
- 100 μL
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实验时间
- 3 - 4 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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缓冲液
- 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- IL-25 (IL25) (Interleukin 25 (IL25))
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别名
- IL-17E
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背景
- Interleukin 17E (IL-17E), also known as IL-25, is a cytokine that belongs to the IL-17 cytokine family and is secreted by type 2 helper T cells (Th2) and mast cells. It shares the sequence similarity with IL-17. This cytokine can induce NF-κB activation, and stimulate the production of IL-8. Both this cytokine and IL-17B are ligands for the cytokine receptor IL-17RB. Studies in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. IL-17E induces the production of other cytokines, including IL-4, IL-5 and IL-13 in multiple tissues, which stimulate the expansion of eosinophils. This cytokine is an important molecule controlling immunity of the gut and has been implicated in chronic inflammation associated with the gastrointestinal tract. IL-17E can kill some types of breast cancer cells.
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NCBI登录号
- NM_022789
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UniProt
- Q9H293
抗原 See all IL-25 (IL25) ELISA试剂盒
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