KREMEN1 ELISA 试剂盒
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Quick Overview for KREMEN1 ELISA 试剂盒 (ABIN5510702)
抗原
See all KREMEN1 ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Kremen-1
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: NSO
Immunogen sequence: A20-G395 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Tissue Specificity: In the adult, widely expressed with high levels in heart, lung, kidney, skeletal muscle and testis. .
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
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别名
- Kremen1
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背景
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Protein Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). .
Background: Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Synonyms: Kremen protein 1,Dickkopf receptor,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,Kremen1,Kremen,
Full Gene Name: Kremen protein 1
Cellular Localisation: Membrane, Single-pass type I membrane protein. -
UniProt
- Q99N43
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途径
- WNT signaling
抗原 See all KREMEN1 ELISA试剂盒
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