GZMB ELISA 试剂盒
Quick Overview for GZMB ELISA 试剂盒 (ABIN5510620)
抗原
See all GZMB ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
-
-
原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Granzyme B
-
品牌
- PicoKine™
-
Analytical Method
- Quantitative
-
特异性
- Expression system for standard: NSO, Immunogen sequence: I21-S247
-
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
-
-
Granzyme B (GZMB) ELISA Kit
GZMB 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granzyme B (GZMB) ELISA KitGZMB 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granzyme B (GZMB) ELISA KitGZMB 适用: 大鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Granzyme B (GZMB) ELISA KitGZMB 适用: 猴 Colorimetric Sandwich ELISA 15.63 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma, Serum
Granzyme B (GZMB) ELISA KitGZMB 适用: 人 AA 21-247 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Granzyme B (GZMB) ELISA KitGZMB 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
-
-
板类型
- Pre-coated
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
-
有效期
- 12 months
-
-
- GZMB (Granzyme B (GZMB))
-
别名
- Gzmb
-
背景
-
Protein Function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). .
Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Synonyms: Granzyme B(G,H),3.4.21.79,CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1,
Full Gene Name: Granzyme B(G,H)
Cellular Localisation: Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells. -
UniProt
- P04187
-
途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原 See all GZMB ELISA试剂盒
-
