电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Cardiotrophin 1 ELISA 试剂盒

CTF1 适用: 小鼠 AA 2-203 Colorimetric Sandwich ELISA
产品编号 ABIN5510574
发货至: 中国
  • 抗原 See all Cardiotrophin 1 (CTF1) ELISA试剂盒
    Cardiotrophin 1 (CTF1)
    抗原表位
    AA 2-203
    适用
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Cardiotrophin-1
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: E.coli, Immunogen sequence: S2-A203
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.

    Featured
    Discover our best selling CTF1 ELISA Kit
    Top Product
    Discover our top product CTF1 ELISA Kit
  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all Cardiotrophin 1 (CTF1) ELISA试剂盒
    Cardiotrophin 1 (CTF1)
    别名
    Ctf1 (CTF1 产品)
    别名
    CTF1 ELISA Kit, ct1 ELISA Kit, ct-1 ELISA Kit, ctf2 ELISA Kit, CT-1 ELISA Kit, CT1 ELISA Kit, cardiotrophin 1 ELISA Kit, cardiotrophin-1 ELISA Kit, CTF1 ELISA Kit, ctf1 ELISA Kit, Ctf1 ELISA Kit, LOC100736818 ELISA Kit
    背景

    Protein Function: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.

    Background: Cardiotrophin-1 (CT-1) is a member of the family of cytokines that includes leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), interleukin-6 (IL6), and interleukin-11 (IL11). And the CT-1 gene is mapped to 1p21-p13. The human CT-1 protein contains 201 amino acids and shares 80 % amino acid identity with the 203-amino acid mouse CT-1 sequence, however, unlike the mouse protein, human CT-1 has 2 rather than 1 cys and has no N-glycosylation site. Despite lacking a signal sequence, secreted CT-1 and mouse CT-1 induce cardiac myocyte hypertrophy in cell culture and bind to both mouse and human LIFR but not to OSMR. Furthermore, A 1.7-kb CT-1 transcript was detected at high levels in heart, skeletal muscle, prostate, and ovary. Low levels were detected in lung, kidney, pancreas, thymus, testis, and small intestine, with little or no expression detected in brain, placenta, spleen, colon, and peripheral blood leukocytes. And it was also observed strong expression in fetal lung and kidney.

    Synonyms: Cardiotrophin-1, CT-1, Ctf1,

    Full Gene Name: cardiotrophin 1

    Cellular Localisation: Secreted.
    UniProt
    Q60753
    途径
    JAK/STAT Signaling
You are here:
客服