IL-25 ELISA 试剂盒
Quick Overview for IL-25 ELISA 试剂盒 (ABIN4986951)
抗原
See all IL-25 (IL25) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 0.03 ng/mL
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Analytical Method
- Quantitative
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特异性
- Natural and recombinant Mouse IL-25(IL-17E) Ligand
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灵敏度
- 15 pg/mL
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试剂未包括
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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应用备注
- Detection Wavelength: 450 nm
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样本量
- 20 μL
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实验时间
- 3 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C
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- IL-25 (IL25) (Interleukin 25 (IL25))
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别名
- IL-25(IL-17E)
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背景
- IL-25 (also known as IL-17E) is a member of the IL-17 family of proinflammatory cytokines, which includes IL-17A, IL-17B, IL-17C, IL-17F and IL-17A/F. IL-17E is found at low levels in various peripheral tissues. It is a proinflammatory cytokine that promotes airway eosinophilia in mice. IL-17E plays a role in Th2 type inflammatory diseases, such as asthma and atopic dermatitis. IL-25 induces elevatedgene expression of IL-4, IL-5 and IL-13 in multiple tissues and results in T helper 2 (TH2)-type immune responses (increased serumIgE levels) and pathologic changes in the lungsand digestive tract with eosinophilic infiltrates, increased mucusproduction, epithelial cell hyperplasia and overall amplified allergicinflammation. IL-25 shares the receptor IL-17RB with IL-17B, although it binds with much higher affinity than IL-17B.
抗原 See all IL-25 (IL25) ELISA试剂盒
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