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IL-25 ELISA 试剂盒

This 小鼠 IL-25 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 IL-25.
产品编号 ABIN4986951
发货至: 中国

Quick Overview for IL-25 ELISA 试剂盒 (ABIN4986951)

抗原

See all IL-25 (IL25) ELISA试剂盒
IL-25 (IL25) (Interleukin 25 (IL25))

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

0.03-2.0 ng/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
  • 最低检测浓度

    0.03 ng/mL

    Analytical Method

    Quantitative

    特异性

    Natural and recombinant Mouse IL-25(IL-17E) Ligand

    灵敏度

    15 pg/mL

    试剂未包括

    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
  • 应用备注

    Detection Wavelength: 450 nm

    样本量

    20 μL

    实验时间

    3 h

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C
  • 抗原 See all IL-25 (IL25) ELISA试剂盒

    IL-25 (IL25) (Interleukin 25 (IL25))

    别名

    IL-25(IL-17E)

    背景

    IL-25 (also known as IL-17E) is a member of the IL-17 family of proinflammatory cytokines, which includes IL-17A, IL-17B, IL-17C, IL-17F and IL-17A/F. IL-17E is found at low levels in various peripheral tissues. It is a proinflammatory cytokine that promotes airway eosinophilia in mice. IL-17E plays a role in Th2 type inflammatory diseases, such as asthma and atopic dermatitis. IL-25 induces elevatedgene expression of IL-4, IL-5 and IL-13 in multiple tissues and results in T helper 2 (TH2)-type immune responses (increased serumIgE levels) and pathologic changes in the lungsand digestive tract with eosinophilic infiltrates, increased mucusproduction, epithelial cell hyperplasia and overall amplified allergicinflammation. IL-25 shares the receptor IL-17RB with IL-17B, although it binds with much higher affinity than IL-17B.
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