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PLAU ELISA 试剂盒

This 人 PLAU ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 PLAU.
产品编号 ABIN2042715
发货至: 中国

Quick Overview for PLAU ELISA 试剂盒 (ABIN2042715)

抗原

See all PLAU ELISA试剂盒
PLAU (Plasminogen Activator, Urokinase (PLAU))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

62.5-4000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    62.5 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 5 pg/mL

    组件

    96-well plate pre-coated with anti-uPA/PLAU, Human
    Lyophilized recombinant uPA/PLAU, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human uPA/PLAU in cell culture supernates, serum and plasma (heparin, EDTA).Plasminogen activator,urokinase (PLAU, uPA) converts plasminogen to plasmin. Plasmin is involved in processing of amyloid precursor protein and degrades secreted and aggregated amyloid-beta, a hallmark of Alzheimer disease (AD). Urokinase has a molecular mass of about 54kD and is composed of 2 disulfide-linked chains, A and B, of molecular masses 18kD and 33kD, respectively. It localized on 10q24. uPA facilitates cell migration by localizing proteolisys on the cell surface and by inducing intracellular signalling pathways. In human vascular smooth muscle cell (VSMC), uPA stimulates migration via the uPA receptor (uPAR) signalling complex containing TYK2 and phosphatidylinositol 3-kinase (PI3-K).

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all PLAU ELISA试剂盒

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    别名

    uPA/PLAU

    基因ID

    5328

    UniProt

    P00749

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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