Survivin ELISA 试剂盒
Quick Overview for Survivin ELISA 试剂盒 (ABIN2042670)
抗原
See all Survivin (BIRC5) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
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最低检测浓度
- 62.5 pg/mL
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交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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灵敏度
- < 2 pg/mL
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组件
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96-well plate pre-coated with anti-Survivin, Human
Lyophilized recombinant Survivin, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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板类型
- Pre-coated
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实验流程
- Sandwich ELISA quantitative detection kit for Human Survivin in cell culture supernates, serum and plasma (heparin, EDTA).Survivin (also termed API4) belongs to the family of genes known as inhibitors of apoptosis, and it has been implicated in both prevention of cell death and control of mitosis. Survivin is prominently expressed in transformed cell lines and in all the most common human cancers of lung, colon, pancreas, prostate and breast in vivo. It is also found in approximately 50% of high-grade non-Hodgkin's lymphomas. Survivin encodes a deduced 142-amino acid protein and localizes on chromosome 17q25. The overexpression of it in cancer may overcome an apoptotic checkpoint and favour aberrant progression of transformed cells through mitosis. The standard product used in this kit is recombinant human Survivin with the molecular mass of 34kD.
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限制
- 仅限研究用
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储存条件
- 4 °C/-20 °C
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- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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基因ID
- 332
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UniProt
- O15392
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途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原 See all Survivin (BIRC5) ELISA试剂盒
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