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MMP2 ELISA 试剂盒

MMP2 适用: 小鼠 Colorimetric Sandwich ELISA 6-10000 pg/mL
产品编号 ABIN2042603
发货至: 中国
  • 抗原 See all MMP2 ELISA试剂盒
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    适用
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    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    6-10000 pg/mL
    最低检测浓度
    6 pg/mL
    应用范围
    ELISA
    品牌
    BioAssay™
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    灵敏度
    < 10 pg/mL
    组件
    96-well plate pre-coated with anti-MMP-2, Mouse
    Lyophilized recombinant MMP-2, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
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  • 板类型
    Pre-coated
    实验流程
    Sandwich ELISA quantitative detection kit for Mouse MMP-2 in cell culture supernates, serum and plasma (heparin).Type IV collagenase, 72kD, is officially designated matrix metalloproteinase-2 (MMP2). It is also known as gelatinase, 72kD. MMP-2 plays an essential role in angiogenesis and arteriogenesis, two processes critical to restoration of tissue perfusion after ischemia. MMP-2 expression is increased in tissue ischemia, but the responsible mechanisms remain unknown.1 Matrix metalloproteinases (MMPs) catalyze extracellular matrix degradation. Control of their activity is a promising target for therapy of diseases characterized by abnormal connective tissue turnover. MMPs are expressed as latent proenzymes that are activated by proteolytic cleavage that triggers a conformational change in the propeptide (cysteine switch). The structure of proMMP-2 reveals how the propeptide shields the catalytic cleft and that the cysteine switch may operate through cleavage of loops essential for propeptide stability.2 The gene is localized to 16q21 using somatic cell hybrids and in situ hybridization.3 The standard product used in this kit is recombinant mouse MMP-2, consisting of 662 amino acids with the molecular mass of 72kD. The detected MMP-2 includes zymogen and active enzyme.
    限制
    仅限研究用
  • 储存条件
    4 °C/-20 °C
  • 抗原 See all MMP2 ELISA试剂盒
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    别名
    MMP-2 (MMP2 产品)
    别名
    2-MMP ELISA Kit, CG1794 ELISA Kit, DM2-MMP ELISA Kit, Dm2-MMP ELISA Kit, Dmel\\CG1794 ELISA Kit, MMP2 ELISA Kit, anon-WO0118547.84 ELISA Kit, dm-2MMP ELISA Kit, dmmp2 ELISA Kit, l(2)02353 ELISA Kit, mmp2 ELISA Kit, wu:fa99h12 ELISA Kit, wu:fk89d01 ELISA Kit, fgmmp-2 ELISA Kit, Mmp-2 ELISA Kit, LOC100135793 ELISA Kit, Clg4a ELISA Kit, GelA ELISA Kit, MMP-2 ELISA Kit, CLG4 ELISA Kit, CLG4A ELISA Kit, MMP-II ELISA Kit, MONA ELISA Kit, TBE-1 ELISA Kit, matrix metallopeptidase 2 ELISA Kit, Matrix metalloproteinase 2 ELISA Kit, matrix metalloproteinase 2 ELISA Kit, matrix metalloproteinase-2 ELISA Kit, MMP2 ELISA Kit, Mmp2 ELISA Kit, mmp2 ELISA Kit, LOC657982 ELISA Kit, LOC100135793 ELISA Kit
    基因ID
    17390
    UniProt
    P33434
    途径
    Activation of Innate immune Response
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