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MICB ELISA 试剂盒

This 人 MICB ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 MICB.
产品编号 ABIN2042594
发货至: 中国

Quick Overview for MICB ELISA 试剂盒 (ABIN2042594)

抗原

See all MICB ELISA试剂盒
MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

62.5-4000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    62.5 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-MICB, Human
    Lyophilized recombinant MICB, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Human MICB in cell culture supernates, serum and plasma (heparin, EDTA).MHC class I polypeptide-related sequence B, also called MICB is a protein that in humans is encoded by the MICB gene. The MICB gene is mapped to 6p21.33. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. It seems to have no role in antigen presentation. This gene acts as a stress-induced self-antigen that is recognized by gamma delta T cells. It is the ligand for the KLRK1/NKG2D receptor and binds to KLRK1 leads to cell lysis.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all MICB ELISA试剂盒

    MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

    别名

    MICB

    基因ID

    4277

    UniProt

    Q29980

    途径

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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