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IGFBP3 ELISA 试剂盒

IGFBP3 适用: 小鼠 Colorimetric Sandwich ELISA 6-10000 pg/mL
产品编号 ABIN2042507
发货至: 中国
  • 抗原 See all IGFBP3 ELISA试剂盒
    IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
    适用
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    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    6-10000 pg/mL
    最低检测浓度
    6 pg/mL
    应用范围
    ELISA
    品牌
    BioAssay™
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    灵敏度
    < 10 pg/mL
    组件
    96-well plate pre-coated with anti-IGFBP-3, Mouse
    Lyophilized recombinant IGFBP-3, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
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  • 板类型
    Pre-coated
    实验流程
    Sandwich ELISA quantitative detection kit for Mouse IGFBP-3 in cell culture supernates and serum.Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is a major determinant of circulating levels of the IGFs and is clinically useful for the evaluation of GH deficiency and for predicting the response to GH treatment. The circulating level of IGFBP-3 is inversely related to the risk of several common cancers, and that antiproliferative agents such as antiestrogens and retinoids act in part by up-regulating IGFBP-3 gene (IGFBP3) expression.1 Insulin-like growth factor-binding protein (IGFBP)-3, well characterized as the carrier of insulin-like growth factor (IGF), has been reported to have intrinsic bioactivity that is independent of IGF binding. IGFBP-3 has an IGF-independent, antiproliferative effect in undifferentiated and early differentiated but not in terminally differentiated chondrocytes.2 IGFBP-3 possesses both growth-inhibitory and potentiating effects on cells that are independent of IGF action and are mediated through specific. IGFBP-3 binding proteins/receptors locate at the cell membrane, cytosol, or nuclear compartments and in the extrIGFBP-3llular matrix.3 IGFBP3 is also located on chromosome 7.4 The standard product used in this kit is recombinant mouse IGFBP-3, consisting of 270 amino acids with the molecular mass of 29.4kD. As a result of glycosylation, the molecular mass is 40-50kD.
    限制
    仅限研究用
  • 储存条件
    4 °C/-20 °C
  • 抗原 See all IGFBP3 ELISA试剂盒
    IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
    别名
    IGFBP-3 (IGFBP3 产品)
    别名
    BP-53 ELISA Kit, IBP3 ELISA Kit, AI649005 ELISA Kit, IGFBP-3 ELISA Kit, IGgfbp3 ELISA Kit, IGF-BP3 ELISA Kit, zgc:91788 ELISA Kit, IGFBP3 ELISA Kit, igfbp3 ELISA Kit, insulin like growth factor binding protein 3 ELISA Kit, insulin-like growth factor binding protein 3 ELISA Kit, IGFBP3 ELISA Kit, Igfbp3 ELISA Kit, igfbp3 ELISA Kit, IGFBP-3 ELISA Kit, LOC100305016 ELISA Kit
    基因ID
    3486
    UniProt
    B3KPF0
    途径
    Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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