FURIN ELISA 试剂盒
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Quick Overview for FURIN ELISA 试剂盒 (ABIN2042473)
抗原
See all FURIN ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
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最低检测浓度
- 2 pg/mL
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交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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灵敏度
- < 10 pg/mL
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组件
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96-well plate pre-coated with anti-Furin, Human
Lyophilized recombinant Furin, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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板类型
- Pre-coated
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实验流程
- Sandwich ELISA quantitative detection kit for Human Furin in cell culture supernates, tissue homogenates and cell lysates.Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance
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限制
- 仅限研究用
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储存条件
- 4 °C/-20 °C
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- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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别名
- Furin
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基因ID
- 5045
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UniProt
- P09958
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
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