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C5A ELISA 试剂盒

This 小鼠 C5A ELISA Kit specifically detects C5A .
产品编号 ABIN2042412
发货至: 中国
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Quick Overview for C5A ELISA 试剂盒 (ABIN2042412)

抗原

See all C5A (C5a) ELISA试剂盒
C5A (C5a) (Complement Component 5a (C5a))

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

15.6-1000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    15.6 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-Complement C5a, Mouse
    Lyophilized recombinant Complement C5a, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Mouse Complement C5a in cell culture supernates, serum and plasma (heparin, EDTA).C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all C5A (C5a) ELISA试剂盒

    C5A (C5a) (Complement Component 5a (C5a))

    别名

    Complement C5a

    基因ID

    15139

    UniProt

    P06684

    途径

    Complement System, Carbohydrate Homeostasis
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