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Endoglin ELISA 试剂盒

ENG 适用: 人 Colorimetric Sandwich ELISA 6-10000 pg/mL
产品编号 ABIN2042388
发货至: 中国
  • 抗原 See all Endoglin (ENG) ELISA试剂盒
    Endoglin (ENG)
    适用
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    6-10000 pg/mL
    最低检测浓度
    6 pg/mL
    应用范围
    ELISA
    品牌
    BioAssay™
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    灵敏度
    < 15 pg/mL
    组件
    96-well plate pre-coated with anti-CD105, Human
    Lyophilized recombinant CD105, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
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  • 板类型
    Pre-coated
    实验流程
    Sandwich ELISA quantitative detection kit for Human CD105 in cell culture supernates, serum and plasma (heparin, EDTA).CD105, also called Endoglin, is a homodimeric membrane glycoprotein primarily associated with human vascular endothelium. It is also found on bone marrow proerythroblasts, activated monocytes, and lymphoblasts in childhood leukemia. Endoglin is a component of the transforming growth factor-beta (TGFB) receptor complex and binds TGFB1 with high affinity.1 CD105 gene is mapped to 9q34.1. The coding region of the gene contains 14 exons.2 The protein consists of a homodimer of 180kDA with disulfide links. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Furthermore, it also has a role in the balance of ALK1 and ALK5 signaling to regulate endothelial cell proliferation.3 Moreover, the elevated expression of endoglin in the surgically excised CNVMs suggested a persisting postmitotic activation in an advanced stage of neovascular tissue.4 The standard product used in this kit is extracellular part of recombinant human CD105, from E26 to G586. As a result of glycosylation, the molecular mass is 75-85kD.
    限制
    仅限研究用
  • 储存条件
    4 °C/-20 °C
  • 抗原 See all Endoglin (ENG) ELISA试剂盒
    Endoglin (ENG)
    别名
    CD105 (ENG 产品)
    别名
    ENG ELISA Kit, MGC137842 ELISA Kit, DKFZp469D0419 ELISA Kit, END ELISA Kit, HHT1 ELISA Kit, ORW1 ELISA Kit, AI528660 ELISA Kit, AI662476 ELISA Kit, CD105 ELISA Kit, S-endoglin ELISA Kit, endoglin ELISA Kit, ENG ELISA Kit, Eng ELISA Kit
    基因ID
    2022
    UniProt
    P17813
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