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Cathepsin B ELISA 试剂盒

CTSB 适用: 人 Colorimetric Sandwich ELISA 6-10000 pg/mL
产品编号 ABIN2042370
发货至: 中国
  • 抗原 See all Cathepsin B (CTSB) ELISA试剂盒
    Cathepsin B (CTSB)
    适用
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    6-10000 pg/mL
    最低检测浓度
    6 pg/mL
    应用范围
    ELISA
    品牌
    BioAssay™
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    灵敏度
    < 5 pg/mL
    组件
    96-well plate pre-coated with anti-Cathepsin B, Human
    Lyophilized recombinant Cathepsin B, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
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  • 板类型
    Pre-coated
    实验流程
    Sandwich ELISA quantitative detection kit for Human Cathepsin B in cell culture supernates, serum and plasma (heparin, EDTA).Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene.1, 2 And this gene is mapped to chromosome 8p22.3 The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of -amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade -amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease.4 Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. The standard product used in this kit is recombinant human Cathepsin B with the molecular mass of 37kD.
    限制
    仅限研究用
  • 储存条件
    4 °C/-20 °C
  • 抗原 See all Cathepsin B (CTSB) ELISA试剂盒
    Cathepsin B (CTSB)
    别名
    Cathepsin B (CTSB 产品)
    别名
    APPS ELISA Kit, CPSB ELISA Kit, CB ELISA Kit, apps ELISA Kit, cpsb ELISA Kit, LOC692390 ELISA Kit, CTSB ELISA Kit, cathepsin B ELISA Kit, cathepsin B S homeolog ELISA Kit, CTSB ELISA Kit, Ctsb ELISA Kit, ctsb.S ELISA Kit, LOC692390 ELISA Kit
    基因ID
    1508
    UniProt
    P07858
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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