电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SensoLyte® 520 Cathepsin B Assay Kit

FRET Fluorometric
产品编号 ABIN1882436
发货至: 中国
  • 抗原 See all Cathepsin B (CTSB) 试剂盒
    Cathepsin B (CTSB)
    检测方法
    Fluorometric
    应用范围
    Fluorescence Resonance Energy Transfer Microscopy (FRET)
    品牌
    SensoLyte®
    产品特性
    The SensoLyte® 520 Cathepsin B Activity Assay Kit provides a QXL™ 520/HiLyte FluorTM 488 labeled FRET peptide substrate for measurement of enzyme activity. In the intact FRET peptide, the fluorescence of HiLyte FluorTM 488 is quenched by QXL™ 520. Upon cleavage of the FRET peptide by the active enzyme, the increase of fluorescence can be continuously monitored at excitation/emission = 490 nm/520 nm. With superior fluorescence quantum yield and longer emission wavelength, the QXL™ 520/HiLyte FluorTM 488 based FRET peptide has less interference from the autofluorescence of test compounds and cellular components and provides better assay sensitivity.
    Top Product
    Discover our top product CTSB ELISA Kit
  • 说明

    FRET-based Assay Kit

    限制
    仅限研究用
  • 注意事项
    Protect Components A and B from light and moisture.
    储存条件
    -80 °C
    储存方法
    Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
  • Unno, Wakamori, Koike, Uchiyama, Ishikawa, Kubota, Yoshida, Sasakawa, Peters, Mizusawa, Watase: "Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 43, pp. 17693-8, (2012) (PubMed).

  • 抗原
    Cathepsin B (CTSB)
    别名
    Cathepsin B (CTSB 产品)
    别名
    APPS Kit, CPSB Kit, CB Kit, apps Kit, cpsb Kit, LOC692390 Kit, CTSB Kit, cathepsin B Kit, cathepsin B S homeolog Kit, CTSB Kit, Ctsb Kit, ctsb.S Kit, LOC692390 Kit
    背景
    Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin B is a member of the cathepsin family consisting of 12 cysteine proteases with broad exo- and endopeptidase activity. Elevated levels of cathepsin B were detected in metastases and neurological disorders including Alzheimer's disease (AD).
You are here:
客服