Caspase 1 ELISA 试剂盒
Quick Overview for Caspase 1 ELISA 试剂盒 (ABIN1168983)
抗原
See all Caspase 1 (CASP1) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 0.15 ng/mL
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Analytical Method
- Quantitative
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特异性
- Detects mouse caspase-1 (proform as well as p10 and p20 domain).
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交叉反应
- 小鼠
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交叉反应 (详细)
- Does not detect human caspase-1.
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灵敏度
- 33 pg/mL
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产品特性
- Standards are full lenght proteins.
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板类型
- Pre-coated
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限制
- 仅限研究用
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注意事项
- Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.
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储存条件
- 4 °C
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储存方法
- After standard reconstitution prepare aliquots and store at -20°C.
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有效期
- 12 months
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: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." in: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).
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: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." in: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).
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- Caspase 1 (CASP1)
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别名
- Caspase-1
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背景
- Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
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UniProt
- P29452
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途径
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原 See all Caspase 1 (CASP1) ELISA试剂盒
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