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Caspase 1 ELISA 试剂盒

This 小鼠 Caspase 1 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 Caspase 1. This ELISA Kit has been cited in1 publication.
产品编号 ABIN1168983
发货至: 中国

Quick Overview for Caspase 1 ELISA 试剂盒 (ABIN1168983)

抗原

See all Caspase 1 (CASP1) ELISA试剂盒
Caspase 1 (CASP1)

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

0.15-10 ng/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Plasma, Serum
  • 最低检测浓度

    0.15 ng/mL

    Analytical Method

    Quantitative

    特异性

    Detects mouse caspase-1 (proform as well as p10 and p20 domain).

    交叉反应

    小鼠

    交叉反应 (详细)

    Does not detect human caspase-1.

    灵敏度

    33 pg/mL

    产品特性

    Standards are full lenght proteins.
  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 注意事项

    Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.

    储存条件

    4 °C

    储存方法

    After standard reconstitution prepare aliquots and store at -20°C.

    有效期

    12 months
  • Miyazaki, Mihara, Inata, Sasaki, Tominaga, Yakura, Ishida, Fukushima, Inoue: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." in: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).

  • 抗原 See all Caspase 1 (CASP1) ELISA试剂盒

    Caspase 1 (CASP1)

    别名

    Caspase-1

    背景

    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.

    UniProt

    P29452

    途径

    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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