This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008].
Gibb, Liu, Natarajan, Santhanakrishnan, Madrid, Eisenbarth, Zimring, Iwasaki, Hendrickson: "Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 3, pp. 1041-1050, (2017) (PubMed).
Aliases for KEL 抗体
Kell blood group (Kel) 抗体 Kell blood group, metallo-endopeptidase (KEL) 抗体 CD238 抗体 Ece3 抗体 ECE3 抗体