KCNQ2 抗体
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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38 results
KCNQ2
适用: 大鼠
FACS, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
Latest Publications for our KCNQ2 抗体
: "Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 9, pp. 3782-93, (2015) (PubMed).: "Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin." in: Biochimica et biophysica acta, Vol. 1852, Issue 9, pp. 1856-66, (2015) (PubMed).
: "K(V)7.4 channels participate in the control of rodent renal vascular resting tone." in: Acta physiologica (Oxford, England), Vol. 214, Issue 3, pp. 402-14, (2015) (PubMed).
: "Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: first evidence for an altered channel regulation by syntaxin-1A." in: Human mutation, Vol. 35, Issue 3, pp. 356-67, (2014) (PubMed).
: "Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit." in: PLoS ONE, Vol. 9, Issue 7, pp. e103655, (2014) (PubMed).
: "Membrane microdomain determines the specificity of receptor-mediated modulation of Kv7/M potassium currents." in: Neuroscience, Vol. 254, pp. 70-9, (2013) (PubMed).
: "Kv7/M-type potassium channels in rat skin keratinocytes." in: Pflügers Archiv : European journal of physiology, Vol. 465, Issue 9, pp. 1371-81, (2013) (PubMed).
: "Functional effects of KCNQ K(+) channels in airway smooth muscle." in: Frontiers in physiology, Vol. 4, pp. 277, (2013) (PubMed).
: "Developmental expression of Kv potassium channels at the axon initial segment of cultured hippocampal neurons." in: PLoS ONE, Vol. 7, Issue 10, pp. e48557, (2012) (PubMed).
: "Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 48, pp. 17637-48, (2011) (PubMed).
Aliases for KCNQ2 抗体
potassium voltage-gated channel subfamily Q member 2 (KCNQ2) 抗体potassium voltage-gated channel, subfamily Q, member 2 (Kcnq2) 抗体
potassium voltage-gated channel subfamily Q member 2 (Kcnq2) 抗体
potassium voltage-gated channel subfamily KQT member 2 (LOC100537363) 抗体
potassium voltage-gated channel, KQT-like subfamily, member 2a (kcnq2a) 抗体
BFNC 抗体
BFNS1 抗体
EBN 抗体
EBN1 抗体
EIEE7 抗体
ENB1 抗体
HNSPC 抗体
KCNA11 抗体
KQT2 抗体
KV7.2 抗体
KVEBN1 抗体
mKQT2.3 抗体
mKQT2.4 抗体
Nmf134 抗体
zgc:171872 抗体
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