Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009].
Gao, Wang, Yan, Zeng, Ma, Niu, Zhou, Jiang, Chen: "Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151118, (2016) (PubMed).
Shigemasa, Gu, Tanimoto, OBrien, Ohama: "Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 8, pp. 2766-70, (2004) (PubMed).
Diamandis, Borgoño, Scorilas, Harbeck, Dorn, Schmitt: "Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients." in: Clinical biochemistry, Vol. 37, Issue 9, pp. 823-9, (2004) (PubMed).
Borgoño, Fracchioli, Yousef, Rigault de la Longrais, Luo, Soosaipillai, Puopolo, Grass, Scorilas, Diamandis, Katsaros: "Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 106, Issue 4, pp. 605-10, (2003) (PubMed).