Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008].
Hu, Yu, Shaw, Pask, Renfree: "Kallmann syndrome 1 gene is expressed in the marsupial gonad." in: Biology of reproduction, Vol. 84, Issue 3, pp. 595-603, (2011) (PubMed).
Tengara, Tominaga, Kamo, Taneda, Negi, Ogawa, Takamori: "Keratinocyte-derived anosmin-1, an extracellular glycoprotein encoded by the X-linked Kallmann syndrome gene, is involved in modulation of epidermal nerve density in atopic dermatitis." in: Journal of dermatological science, Vol. 58, Issue 1, pp. 64-71, (2010) (PubMed).