JUP 抗体
(Junction Plakoglobin (JUP))
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene\; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008].
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Latest Publications for our JUP 抗体
: "Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo." in: The FEBS journal, Vol. 284, Issue 11, pp. 1657-1671, (2017) (PubMed).: "Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch." in: Cancer research, Vol. 69, Issue 14, pp. 5734-42, (2009) (PubMed).
: "Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion." in: The Journal of comparative neurology, Vol. 499, Issue 6, pp. 979-89, (2007) (PubMed).
: "Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7391-402, (2003) (PubMed).
: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).
: "Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5846-58, (2002) (PubMed).
: "Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line." in: Oncogene, Vol. 21, Issue 26, pp. 4108-19, (2002) (PubMed).
: "Reduced expression of plakoglobin correlates with adverse outcome in patients with neuroblastoma." in: The American journal of pathology, Vol. 159, Issue 1, pp. 43-9, (2001) (PubMed).
: "gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin." in: Genes & development, Vol. 14, Issue 11, pp. 1319-31, (2000) (PubMed).
: "Phosphorylation and free pool of beta-catenin are regulated by tyrosine kinases and tyrosine phosphatases during epithelial cell migration." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10173-83, (1999) (PubMed).
Aliases for JUP 抗体
junction plakoglobin (JUP) 抗体junction plakoglobin (Jup) 抗体
junction plakoglobin (jup) 抗体
junction plakoglobin L homeolog (jup.L) 抗体
junction plakoglobin (Tsp_06656) 抗体
Junction plakoglobin (plak) 抗体
junction plakoglobin a (jupa) 抗体
junction plakoglobin S homeolog (jup.S) 抗体
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ctnng 抗体
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dp3 抗体
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jup 抗体
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pdgb 抗体
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plak 抗体
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