JHDM1D 抗体
(Jumonji C Domain-Containing Histone Demethylase 1 Homolog D (JHDM1D))
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate (By similarity).
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24 results
JHDM1D
适用: 人, 小鼠, 大鼠, 犬, 兔, 小鸡, Cow, 豚鼠, 马, Pig
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our JHDM1D 抗体
: "Decreased expression of JHDMID in placenta is associated with preeclampsia through HLA-G." in: Journal of human hypertension, Vol. 32, Issue 6, pp. 448-454, (2018) (PubMed).Aliases for JHDM1D 抗体
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im:7141664 抗体
Jhdm1d 抗体
JHDM1D 抗体
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kdm7 抗体
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