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ISR-alpha 抗体

(Insulin Receptor alpha (ISR-alpha))
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured ISR-alpha Categories

ISR-alpha 抗体

High quality antibodies with extensive validation data.

Recommended ISR-alpha 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
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Cat. No. ABIN7074298
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application IF (cc), IF (p), WB, IHC (p), FACS, ELISA, IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN724145
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application IF (cc), IF (p), IHC (p), ELISA, IHC (fro)
Validations
  • (1)
Cat. No. ABIN726965
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ISR-alpha Products

Xiao, Ma, Zhao, Smith, Huang, Jones, Persaud, Pingitore, Dorling, Lechler, Lombardi: "APT070 (mirococept), a membrane-localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model." in: British journal of pharmacology, Vol. 173, Issue 3, pp. 575-87, (2016) (PubMed).

Synonyms and alternative names related to ISR-alpha

insulin receptor (INSR), CD220, HHF5

Protein level used designations for ISR-alpha

  • IR
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