IRS2 抗体
(Insulin Receptor Substrate 2 (IRS2))
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008].
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Latest Publications for our IRS2 抗体
: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).: "Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 17, Issue 1, pp. 255-264, (2016) (PubMed).
: "Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2." in: Cell cycle (Georgetown, Tex.), Vol. 6, Issue 6, pp. 705-13, (2007) (PubMed).
: "Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45304-7, (2004) (PubMed).
: "IRS proteins and the common path to diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 283, Issue 3, pp. E413-22, (2002) (PubMed).
: "IRS proteins and beta-cell function." in: Diabetes, Vol. 50 Suppl 1, pp. S140-5, (2001) (PubMed).
Aliases for IRS2 抗体
insulin receptor substrate 2 (IRS2) 抗体insulin receptor substrate 2a (irs2a) 抗体
insulin receptor substrate 2b (irs2b) 抗体
insulin receptor substrate 2 (Irs2) 抗体
4PS 抗体
IRS-2 抗体
Irs-2 抗体
IRS2 抗体
si:dkeyp-24d6.1 抗体
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