IRGM 抗体
(Immunity-Related GTPase Family, M (IRGM))
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.[provided by RefSeq, Oct 2010].
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Latest Publications for our IRGM 抗体
: "Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. ..." in: Nature genetics, Vol. 40, Issue 6, pp. 710-2, (2008) (PubMed).: "Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease." in: Autophagy, Vol. 3, Issue 6, pp. 649-51, (2007) (PubMed).
: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).
Aliases for IRGM 抗体
immunity-related GTPase family M member 1 (Irgm1) 抗体immunity-related GTPase M (Irgm) 抗体
immunity related GTPase M (IRGM) 抗体
immunity-related GTPase family M protein (LOC481473) 抗体
Ifi1 抗体
IFI1 抗体
Iigp3 抗体
Iipg3 抗体
Irgm 抗体
IRGM1 抗体
LRG-47 抗体
LRG47 抗体
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