IRF6 抗体
(Interferon Regulatory Factor 6 (IRF6))
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011].
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Latest Publications for our IRF6 抗体
: "IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages." in: Endocrinology, Vol. 158, Issue 9, pp. 2837-2847, (2017) (PubMed).: "TGFβ3 regulates periderm removal through ΔNp63 in the developing palate." in: Journal of cellular physiology, Vol. 230, Issue 6, pp. 1212-25, (2015) (PubMed).
: "Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice." in: Development (Cambridge, England), Vol. 140, Issue 6, pp. 1220-30, (2013) (PubMed).
: "Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 33, pp. 13710-5, (2011) (PubMed).
: "A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias." in: The Journal of clinical investigation, Vol. 120, Issue 5, pp. 1570-7, (2010) (PubMed).
: "Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2235-43, (2008) (PubMed).
: "Interferon regulatory factor 6 (IRF6) is associated with oral-facial cleft in individuals that originate in South America." in: American journal of medical genetics. Part A, Vol. 143A, Issue 17, pp. 2075-8, (2007) (PubMed).
: "Suggestive linkage to a neighboring region of IRF6 in a cleft lip and palate multiplex family." in: American journal of medical genetics. Part A, Vol. 143A, Issue 22, pp. 2716-21, (2007) (PubMed).
: "Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. ..." in: Nature genetics, Vol. 32, Issue 2, pp. 285-9, (2002) (PubMed).
Aliases for IRF6 抗体
interferon regulatory factor 6 (IRF6) 抗体interferon regulatory factor 6 (irf6) 抗体
interferon regulatory factor 6 S homeolog (irf6.S) 抗体
interferon regulatory factor 6 (Irf6) 抗体
AI876454 抗体
DKFZp469E012 抗体
E230028I05Rik 抗体
IRF6 抗体
lps 抗体
LPS 抗体
mirf6 抗体
ofc6 抗体
OFC6 抗体
pit 抗体
PIT 抗体
pps 抗体
PPS 抗体
PPS1 抗体
vws 抗体
VWS 抗体
VWS1 抗体
xIRF-6 抗体
zgc:63500 抗体
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