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- 应用范围
- Activation (Act)
- 原理
- Antioxidant, SIRT1 activator
- 产品特性
- Naturally occurring phenolic antioxidant. Displays antitumor and antiplatelet effects. Activates SIRT1 and increases longevity in yeast. Ameliorates ageing-related phenotypes by inhibition of cAMP phosphodiesterases. Stimulates increased expression of transthyretin which binds Aβ peptide and prevents its aggregation and toxicity. Attenuates Aβ-induced neurotoxicity by induction of autophagy. Rescues SIRT1-dependent adult stem cell decline.
- 纯度
- >98 %
- Chemical Name
- 3,4',5-Trihydroxy-trans-stilbene
- Formula
- C14H12O3
- Solubility
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
PiceatannolInh 10083-24-6 3,3',4,5'-Tetrahydroxy-trans-stilbene
Santacruzamate AInh 1477949-42-0 N-[4-Oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester
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- 限制
- 仅限研究用
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- 状态
- Powder
- 储存条件
- -20 °C
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- 背景
- 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol,Cell cycle,Epigenetics,Coagulation,Apoptosis inhibitor,Apoptosis inducer,Protein deacetylase,Antioxidant,Stem cells,Cell death,Immunology,Diabetes,Cancer,Neurodegeneration,Inflammation,Redox,Ageing,Chromatin
- 分子量
- 228.3
- CAS-编号
- 501-36-0
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