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AR-A014418

InhA, Func 487021-52-3
产品编号 ABIN5678136
发货至: 中国

Quick Overview for AR-A014418 (ABIN5678136)

应用范围

Inhibition Assay (InhA), Functional Studies (Func)
  • 原理

    AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki of 104 nM and 38 nM in cell-free assays, without significant inhibition on 26 other kinases tested.

    产品特性

    Target: GSK-3 inhibitor
    Receptor: GSK3β

    纯化方法

    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

    纯度

    98 %

    Formula

    C12H12N4O4S

    Solubility

    100 mM in DMSO
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Solid

    储存条件

    -20 °C

    储存方法

    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

    有效期

    24 months
  • 背景

    PI3K/Akt/mTOR Signaling

    分子量

    308.31 g/mol

    CAS-编号

    487021-52-3
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