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BMS-754807

InhA, Func 1001350-96-4
产品编号 ABIN4877233
发货至: 中国
  • 应用范围
    Inhibition Assay (InhA), Functional Studies (Func)
    原理
    BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
    产品特性
    Target: IGF-1R inhibitor, c-MET inhibitor, Aurora Kinase inhibitor, FLT3 inhibitor, JAK inhibitor
    Receptor: IGF-1R, Insulin Receptor,TrkB,Met,TrkA,Aurora A,Aurora B,RON,FLT3,JAK2
    纯化方法
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    纯度
    97 % +
    Formula
    C23H24FN9O
    Solubility
    200 mM in DMSO and ethanol
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Solid
    储存条件
    -20 °C
    储存方法
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    有效期
    24 months
  • 背景
    JAK/STAT Signaling,Tyrosine Kinase/Adaptors
    分子量
    461.49 g/mol
    CAS-编号
    1001350-96-4
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