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Capsaicin

Inh 404-86-4 (6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide, 8-Methyl-N-vanillyl-trans-6-nonenamide
产品编号 ABIN1027919
发货至: 中国
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Quick Overview for Capsaicin (ABIN1027919)

应用范围

Inhibition (Inh)

Chemical Name

(6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide, 8-Methyl-N-vanillyl-trans-6-nonenamide
  • 原理

    TRPV1 opener

    产品特性

    TRPV1opener.

    纯度

    >60 % (HPLC), NMR (conforms)

    Formula

    C18H27NO3

    Solubility

    Soluble in DMSO (20 mg/mL) and ethanol (15 mg/mL)
  • 说明

    Source: Synthetic.
    Appearance: Off-White Solid

    限制

    仅限研究用
  • 状态

    Solid

    注意事项

    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R25-37/38-41-42/43 Hazard Phrases: H301-H311-H315-H317-H318-H334-H335 Precautionary Phrases: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311

    注意事项

    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R25-37/38-41-42/43 Hazard Phrases: H301-H311-H315-H317-H318-H334-H335 Precautionary Phrases: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311

    储存条件

    -20 °C
  • 背景

    Capsaicin is an agonist at the TRPV1 receptor, a ligand-gated non-selective cation channel. It exhibits neuroprotective effects in a model of transient global cerebral ischemia and induces release of substance P from afferent nociceptive specific neurons. Powerful excitant of peripheral sensory nerve endings, specifically unmyelinated afferent neurons (C-fibers). Reversibly inhibits aggregation of platelets.

    分子量

    305.41

    CAS-编号

    404-86-4
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