Trichostatin A
Quick Overview for Trichostatin A (ABIN1027849)
应用范围
Chemical Name
-
-
原理
- HDAC inhibitor
-
产品特性
- Histone deacetylase inhibitor.
-
纯度
- >98 %
-
Formula
- C17H22N2O3
-
Solubility
- Soluble to 10 mM in ethanol and to 50 mM in DMSO
-
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Anacardic AcidInh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
AS-8351Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone
UNC-0379Inh 1620401-82-2 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)-pentyl)quinazolin-4-amine
-
-
说明
-
Source: Synthetic.
Appearance: Beige Solid -
限制
- 仅限研究用
-
-
-
状态
- Solid
-
注意事项
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H302-H312-H315-H317-H319-H332-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338
-
注意事项
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H302-H312-H315-H317-H319-H332-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338
-
储存条件
- -20 °C
-
-
-
背景
- Trichostatin A is an antifungal and selectively inhibits the class I and II mammalian histon deacetlyase families of enzymes. TSA inhibits the eukayotic cell cycle during the beginning of the growth stage. It can be used to alter gene expression but interfering with the removal of acetyl groups thereby altering the ability of DNA transcription factors to access the DNA inside chromatin. It also has anti-cancer properties
-
分子量
- 302.37
-
CAS-编号
- 58880-19-6
-
-
