Trichostatin A
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- 应用范围
- Inhibition (Inh)
- 原理
- HDAC inhibitor
- 产品特性
- Histone deacetylase inhibitor.
- 纯度
- >98 %
- Chemical Name
- (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
- Formula
- C17H22N2O3
- Solubility
- Soluble to 10 mM in ethanol and to 50 mM in DMSO
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
PiceatannolInh 10083-24-6 3,3',4,5'-Tetrahydroxy-trans-stilbene
Santacruzamate AInh 1477949-42-0 N-[4-Oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester
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- 说明
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Source: Synthetic.
Appearance: Beige Solid - 限制
- 仅限研究用
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- 状态
- Solid
- 注意事项
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H302-H312-H315-H317-H319-H332-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338
- 注意事项
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H302-H312-H315-H317-H319-H332-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338
- 储存条件
- -20 °C
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- 背景
- Trichostatin A is an antifungal and selectively inhibits the class I and II mammalian histon deacetlyase families of enzymes. TSA inhibits the eukayotic cell cycle during the beginning of the growth stage. It can be used to alter gene expression but interfering with the removal of acetyl groups thereby altering the ability of DNA transcription factors to access the DNA inside chromatin. It also has anti-cancer properties
- 分子量
- 302.37
- CAS-编号
- 58880-19-6
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